What is PRP and what can you expect from it?
Platelet-rich plasma uses a concentration of platelets obtained from your own blood. It may help control symptoms in selected patients, but it is not a universal solution and does not rebuild a damaged joint on its own.
Dr. Gustavo Álvarez6 min readSeptember 28, 2026What PRP is
Platelet-rich plasma, or PRP, is prepared from a sample of the patient’s own blood. The blood is spun to separate and concentrate platelets, which contain proteins and biological factors involved in tissue repair.
The preparation is injected into the indicated area. Its final composition can vary by preparation system, so not every treatment called PRP is exactly the same.
When it may be considered
Evidence is not the same for every injury. In orthopaedics, PRP may be considered as part of care for some cases of mild to moderate knee osteoarthritis and certain chronic tendon injuries. The decision depends on diagnosis, age, activity level, and previous treatments.
- Pain from knee osteoarthritis that is not advanced.
- Some persistent tendinopathies that have not improved with an appropriate rehabilitation program.
- Selected cases where the goal is to complement—not replace—physical therapy and load management.
What to expect afterward
The injection is usually an outpatient procedure. Temporary pain, pressure, or swelling may occur during the first few days. The follow-up plan may include relative rest and a gradual return to mobility and strengthening exercises.
Response is neither immediate nor identical for everyone. When there is a benefit, it is usually assessed by reduced pain and improved function over the following weeks.
What PRP cannot promise
PRP cannot guarantee cartilage regeneration, prevent surgery, or cure every injury. It also cannot correct major mechanical problems such as marked instability, a complete tear, or advanced osteoarthritis.
A responsible recommendation starts with a specific diagnosis and explains the reasonable outcome, available alternatives, and how response will be measured.
Useful questions before deciding
- What is my exact diagnosis and what would PRP aim to achieve?
- What evidence supports its use for this specific injury?
- How is the preparation made and delivered?
- What rehabilitation will I need afterward?
- What risks, costs, and alternatives should I consider?
This article is educational and does not replace a medical evaluation. The indication and results of PRP depend on the diagnosis and each patient’s characteristics.